MODULE 05 / REFERENCES

Full Bibliography

Every citation referenced across this course, with DOIs, PubMed links, and study-type classification.

Bibliography

All citations are drawn directly from peer-reviewed publications accessible via PubMed, PubMed Central, or publisher DOI. The table below is sortable by year, author, journal, and study type. Study types are classified as: PRECLINICAL (rodent or other animal in vivo), IN VITRO (cell culture), HUMAN PILOT, REVIEW, or PHARMACOKINETIC.

Outbound links on this page lead to PubMed, PubMed Central, and publisher sites. This is the only page on this site with external outbound links; they are restricted to primary sources.

All 16 numbered citations below correspond to the inline [N] citations used across the course modules.

  1. Brcic L, Brcic I, Staresinic M, Novinscak T, Sikiric P, Seiwerth S. Modulatory effect of gastric pentadecapeptide BPC 157 on angiogenesis in muscle and tendon healing. Journal of Physiological Pharmacology. 2009.
  2. Krivic A, Anic T, Seiwerth S, Huljev D, Sikiric P. Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: Promoted tendon-to-bone healing and opposed corticosteroid aggravation. Journal of Orthopaedic Research. 2006.
  3. Chang CH, Tsai WC, Hsu YH, Pang JH. Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts. Molecules. 2014;19(11):19066-19077.
  4. Seiwerth S, Milavic M, Vukojevic J, Gojkovic S, Krezic I, et al. Stable Gastric Pentadecapeptide BPC 157 and Wound Healing. Frontiers in Pharmacology. 2021.
  5. Vukojevic J, Vrdoljak B, Malekinusic D, Siroglavic M, Milavic M, Kolenc D, et al. The effect of pentadecapeptide BPC 157 on hippocampal ischemia/reperfusion injuries in rats. Brain and Behavior. 2020.
  6. Perovic D, Kolenc D, Bilic V, Somun N, Drmic D, Elabjer E, Buljat G, Seiwerth S, Sikiric P. Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats. Journal of Orthopaedic Surgery and Research. 2019.
  7. Vukojevic J, Milavic M, Perovic D, Ilic S, et al. Pentadecapeptide BPC 157 and the central nervous system. Neural Regeneration Research. 2022.
  8. Udovicic M, Sever M, Kavur L, Loncaric K, Barisic I, Balenovic D, et al. Stable Gastric Pentadecapeptide BPC 157 Therapy for Monocrotaline-Induced Pulmonary Hypertension in Rats Leads to Prevention and Reversal. Biomedicines. 2021.
  9. Sikiric P, Skrtic A, Gojkovic S, Krezic I, Zizek H, Lovric E, et al. Cytoprotective gastric pentadecapeptide BPC 157 resolves major vessel occlusion disturbances, ischemia-reperfusion injury following Pringle maneuver, and Budd-Chiari syndrome. World Journal of Gastroenterology. 2022.
  10. He L, Feng D, Guo H, Zhou Y, Li Z, Zhang K, et al. Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs. Frontiers in Pharmacology. 2022.
  11. Sikiric P, Seiwerth S, Skrtic A, Staresinic M, et al. Stable Gastric Pentadecapeptide BPC 157 as a Therapy and Safety Key: A Special Beneficial Pleiotropic Effect Controlling and Modulating Angiogenesis and the NO-System. Pharmaceuticals (Basel). 2025.
  12. Matek D, Matek I, Staresinic E, Japjec M, Bojanic I, Boban Blagaic A, et al. Stable Gastric Pentadecapeptide BPC 157 as Therapy After Surgical Detachment of the Quadriceps Muscle from Its Attachments for Muscle-to-Bone Reattachment in Rats. Pharmaceutics. 2025.
  13. McGuire FP, Martinez R, Lenz A, Skinner L, Cushman DM. Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing. Current Reviews in Musculoskeletal Medicine. 2025.
  14. Demirtas H, Ozer A, Yildirim AK, Dursun AD, Sezen SC, Arslan M. Protective Effects of BPC 157 on Liver, Kidney, and Lung Distant Organ Damage in Rats with Experimental Lower-Extremity Ischemia-Reperfusion Injury. Medicina (Kaunas). 2025.
  15. Vukusic D, Zenko Sever A, Sever M, Drmic D, Milavic M, Sikiric S, et al. Duodenocolic fistula healing by pentadecapeptide BPC 157 in rats. A cytoprotection viewpoint. Journal of Physiology and Pharmacology. 2024.
  16. Yuan C, Demers A, Silva-Ortiz V, Hasoon JJ, Lee W, Dave K, Amirdelfan K, Burke HW, Christo PJ, Robinson CL. From Regeneration to Analgesia: The Role of BPC-157 in Tissue Repair and Pain Management. International Journal of Molecular Sciences. 2026.
  17. Lee E, Burgess K. Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study. Alternative Therapies in Health and Medicine. 2025.
  18. Lee E, Walker C, Ayadi B. Effect of BPC-157 on Symptoms in Patients with Interstitial Cystitis: A Pilot Study. Alternative Therapies in Health and Medicine. 2024.
  19. Lee E, Padgett B. Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain. Alternative Therapies in Health and Medicine. 2021.
  20. Hsieh MJ, et al. Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation. Journal of Molecular Medicine (Berlin). 2017;95:323-333.
  21. Author group. BPC 157 Therapy: Targeting Angiogenesis and Nitric Oxide's Cytotoxic and Damaging Actions. Pharmaceuticals (Basel). 2025;18:1450.
  22. Tohyama Y, et al. Effects of pentadecapeptide BPC157 on regional serotonin synthesis in the rat brain: alpha-methyltryptophan autoradiographic measurements. Life Sciences. 2004;76:345-357.
  23. Boban Blagaic A, et al. Gastric pentadecapeptide BPC 157 effective against serotonin syndrome in rats. European Journal of Pharmacology. 2005;512:173-179.